A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 41/00 (2006.01) A61K 31/197 (2006.01) A61N 5/067 (2006.01)
Patent
CA 2422865
Light treatments of sebaceous gland disorders with 5-aminolevulinic acid and photodynamic therapy are disclosed. A preferred treatment includes topical application of 5-aminolevulinic acid to the skin followed by light exposures with repeated treatment at various intervals. At low doses of ALA and photodynamic therapy (PDT) in single or multiple treatments, improvement in the sebaceous gland disorder, e.g., acne, provides the discovery that diminishment in sebum secretion and the eradication of bacteria occurs. At high doses of ALA and a single high energy PDT treatment, permanent changes to the sebaceous gland and sebum secretion have been discovered.
L'invention concerne des photothérapies de troubles des glandes sébacées par une thérapie photodynamique à l'acide 5-aminolévulinique. Un traitement préféré comprend l'application topique d'acide 5-aminolévulinique sur la peau, suivie d'expositions à la lumière, le traitement étant répété à des intervalles variés. A faibles doses d'ALA accompagnées d'un ou de plusieurs traitements par thérapie photodynamique (TPD), on observe une amélioration du trouble des glandes sébacées, tel que l'acné, dénotant une diminution de la sécrétion de sébum et l'éradication des bactéries. A fortes doses d'ALA accompagnées d'un traitement unique haute énergie par TPD, on constate des changements permanents au niveau des glandes sébacées et de la sécrétion de sébum.
Riches Mckenzie & Herbert Llp
The General Hospital Corporation D/b/a Massachusetts General Hos
LandOfFree
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