Aminoluciferin derivatives, processes for the production...

Details Aminoluciferin derivatives, processes for the production... Aminoluciferin derivatives, processes for the production...

C - Chemistry, Metallurgy

07

D

260/228, 530/5.0

C07D 277/68 (2006.01) C07D 277/64 (2006.01) C07H 17/00 (2006.01) C07K 5/04 (2006.01) C07K 5/06 (2006.01) C07K 5/08 (2006.01) C07K 5/10 (2006.01) C12Q 1/37 (2006.01) C12Q 1/56 (2006.01) C12Q 1/66 (2006.01) G01N 33/535 (2006.01)

Patent

CA 1311333

Abstract The invention relates to D-aminoluciferin derivatives of the general formula I Image (I) wherein R1 represents a L-amino acid or peptide radical having up to 10 L-amino acid moieties said radical being bound via the (terminal) carboxyl group in the form of an amide and the free amino group thereof is optionally be protected by a common protecting group, or wherein R1 represents a monosaccharide or disaccharide radical. Said aminoluciferin derivatives can be cleaved by enzymes giving free aminoluciferin which can be determined lumino- metrically. The invention relates also to the use of said aminoluciferin derivatives for determining enzyme activities as well to a process for producing said aminoluciferin derivatives.

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