Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful...

Details Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful... Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful...

C - Chemistry, Metallurgy

07

D

167/208, 260/266

C07D 263/22 (2006.01) A61K 31/42 (2006.01) C07D 263/20 (2006.01) C07D 413/10 (2006.01)

Patent

CA 1320730

BP-6326 Title AMINOMETHYL OXOOXAZOLIDINYL AROYLBENZENE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS Abstract of the Disclosure An antibacterial compound having the formula: Image wherein for the ? isomer or racemic mixtures containing it Image u is 1 or 2; R3 is H, alkyl of 1-10 carbon atoms, or cycloalkyl of 3-8 carbon atoms; R4 is H, alkyl of 1-4 carbon atoms, alkenyl of 2-4 carbon atoms, cycloalkyl of 3-4 carbon atoms, or OR5; R5 is alkyl of 1-4 carbon atoms; R1 ant R2 taken together are H2, H and OH, =O, =NOH, H and N(R6)2, =NOR5, =NO?R4 or Image ; R6 is H or alkyl of 1-4 carbon atoms; X is pyridinyl or phenyl optionally substituted with from 1-3 substituents each independently selected from a group selected from halogen, alkyl of 1-4 carbon atoms, NO2, ORs, or S(O)mRs; and m is 0, 1 or 2; or a pharmaceutically suitable salt thereof.

579796

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