Aminomethyltriorganotin compounds, .alpha.-mono or...

Details Aminomethyltriorganotin compounds, .alpha.-mono or... Aminomethyltriorganotin compounds, .alpha.-mono or...

C - Chemistry, Metallurgy

07

F

260/279.3, 260/2

C07F 7/22 (2006.01)

Patent

CA 1252104

A B S T R A C T The invention concerns a method of preparation of aminomethyltriorganotin compounds, preferably .alpha.-mono or disubstituted, the new tin compounds obtained thereby and an application of said tin compounds to the synthesis of aminomethylorganometallic compounds and to the regiospeci- fic preparation of .beta.-aminoalcohols. The intermediate tin and metallic compounds are new. The method for preparing the tin compounds comprises reacting an iminium salt with a corresponding stannylanion, preferably a triorganostannyl- anion. This method provides best yields and provides regio- specific .beta.-aminoalcohols useful by having in most cases a large spectrum of pharmacological activities.

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