Aminophenyl derivatives as novel inhibitors of histone...

Details Aminophenyl derivatives as novel inhibitors of histone... Aminophenyl derivatives as novel inhibitors of histone...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/4439 (2006.01) A61K 31/506 (2006.01) A61P 17/06 (2006.01) A61P 35/00 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2631876

This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions 15 containing them and their use as a medicine.

Cette invention concerne de nouveaux composés de formule (I) dans laquelle R1, R2, R3, R4, R5, R6, R7, R8, R9, X et Y ont les correspondances indiquées, ces composés ayant une activité enzymatique d'inhibition d'histone désacétylase ; leur préparation, des compositions les contenant, et leur utilisation en tant que médicament.

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