Aminophenyl derivatives as selective androgen receptor...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 451/02 (2006.01) A61K 31/435 (2006.01) A61P 3/04 (2006.01) A61P 5/26 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2594340

Disclosed herein is a novel class of aminophenyl compounds having the structure (I) wherein R1 is cyano or nitro and ring A is a bi- or tricyclic bridged heterocycle and to their use as modulators of androgen receptor for the treatment or prevention of conditions relating thereto.

L'invention concerne une nouvelle classe de composés d'aminophényle possédant la structure (I) dans laquelle R1 est cyano ou nitro, et le noyau A est un hétérocycle à passerelle bi- ou tricyclique, et leur utilisation en tant que modulateurs de récepteurs d'androgènes destinés au traitement ou à la prévention des états pathologiques correspondants.

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