Aminophenylpropanoic acid derivative

Details Aminophenylpropanoic acid derivative Aminophenylpropanoic acid derivative

C - Chemistry, Metallurgy

07

D

C07D 335/02 (2006.01) A61K 31/196 (2006.01) A61K 31/343 (2006.01) A61K 31/382 (2006.01) A61K 31/4015 (2006.01) A61K 31/415 (2006.01) A61K 31/426 (2006.01) A61P 3/10 (2006.01) C07C 229/42 (2006.01) C07C 317/18 (2006.01) C07D 207/26 (2006.01) C07D 231/12 (2006.01) C07D 277/42 (2006.01) C07D 307/80 (2006.01)

Patent

CA 2560111

A compound represented by the formula (1) (wherein the symbols are the same as defined in the description), a salt thereof, and a prodrug thereof. They unexpectedly have excellent GPR40 receptor agonistic activity and are excellent in properties required of medicines, such as stability. They can be a medicine which is safe and useful as a preventive/therapeutic agent for pathological states or diseases in which a GPR40 receptor participates, such as diabetes.

Composé représenté par la formule (1) (dans laquelle les symboles sont les mêmes que ceux définis dans la description), sel de celui-ci et promédicament de celui-ci. Ils ont de façon inattendue une excellente activité agoniste vis-à-vis du récepteur GPR40 et sont excellents en termes de propriétés requises pour des médicaments, telles que la stabilité. Ils peuvent constituer un médicament qui est sans danger et utile comme agent préventif/thérapeutique pour des états pathologiques ou des maladies dans lesquels participe un récepteur GPR40, tels que des diabètes.

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