C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/14 (2006.01) A61K 31/381 (2006.01) C07D 333/16 (2006.01)
Patent
CA 2590939
The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation.
L'invention concerne des composés d'aminopyrimidine utiles dans le traitement de maladies induites par la kinase 1 de type polo (Plk1). Cette invention concerne également l'utilisation thérapeutique de ces composés et des compositions de ceux-ci dans le traitement d'état pathologiques associés à la croissance cellulaire anormale et la prolifération cellulaire non désirée.
Brennan Paul Edward
Demorin Frenel Fils
Liu Gang
Paras Nick A.
Rainbeau Elizabeth
Amgen Inc.
Gowling Lafleur Henderson Llp
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