C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/42 (2006.01) A61P 3/00 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2633740
A compound of formula 1 efficiently inhibit several protein kinases including glycogen synthase kinase 3 (GSK), aurora kinase, extracellular signal- regulated kinase (ERK), protein kinase B (AKT), and the likes, to control signal transductions involved in variable disorders such as diabetes, obesity, dementia, cancer, and inflammation.
La présente invention concerne un composé de formule (1) inhibiteur efficace de plusieurs protéines kinases, comprenant la glycogène synthase kinase 3 (GSK), la kinase Aurora, la kinase régulée par un signal extracellulaire (ERK), la protéine kinase B (AKT), et analogues, pour le contrôle de transductions de signal impliquées dans divers troubles tels que le diabète, l'obésité, la démence, le cancer, et l'inflammation.
Cho Joong Myung
Kim Cheol Min
Lee Do Young
Lee Mi Jung
Lee Seung Chul
Cassan Maclean
Crystalgenomics Inc.
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