C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/53 (2006.01) A61K 51/04 (2006.01) A61K 51/12 (2006.01) C07B 59/00 (2006.01) C07D 213/38 (2006.01) C07F 5/00 (2006.01) C07F 7/22 (2006.01) C07F 13/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) G01N 33/50 (2006.01) G01N 33/60 (2006.01)
Patent
CA 2225861
A compound is provided of formula (I) wherein n is 4-16, Det is an organic group comprising a radioisotope or capable of chelating a radioisotope, and Z- is one equivalent of a biologically acceptable anion, which compounds are useful to radiolabel cellular membranes, as of hematopoietic cells.
L'invention se rapporte à des composés du type représenté par la formule (I). Dans ladite formule, n est compris entre 4 et 16, Det est un groupe organique comprenant un radioisotope ou capable de soumettre un radioisotope à une chélation, et Z?-¿ est un équivalent d'un anion biologiquement acceptable. Les composés de ce type sont utiles pour le radiomarquage des membranes cellulaires, par exemple celles des cellules hématopoïétiques.
Lambert Carol
Mcafee John G.
Mease Ronnie C.
Gowling Lafleur Henderson Llp
Research Corporation Technologies Inc.
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