Aminosugar, glycosaminoglycan, and s-adenosylmethionine...

Details Aminosugar, glycosaminoglycan, and s-adenosylmethionine... Aminosugar, glycosaminoglycan, and s-adenosylmethionine...

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 31/715 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2333752

A composition for the protection, treatment and repair and for reducing the inflammation of connective tissue in mammals and a method for the treatment of connective tissue in mammals by the administration of the composition. The composition includes S-Adenosylmethionine (SAM), and a component selected from an aminosugar or salts thereof (e.g., glucosamine) or glycosaminoglycans (e.g., chondroitin salts) or mixtures or fragments thereof. The composition optionally includes manganese which promotes the production of connective tissue matrix. The composition also optionally includes methyl donors or methyl donor cofactors, such as vitamin B12, vitamin B6, folic acid, dimethylglycine or trimethylglycine.

Cette invention se rapporte à une composition servant à la protection, au traitement et à la réparation des tissus conjonctifs et servant à réduire l'inflammation de ces tissus conjonctifs chez des mammifères, ainsi qu'à un procédé de traitement des tissus conjonctifs chez des mammifères par administration de cette composition. Celle-ci contient de la S-adénosylméthionine (SAM), ainsi qu'un constituant choisi parmi un aminosucre ou des sels de celui-ci (par exemple glucosamine) ou des glycosaminoglycanes (par exemple des sels de chondroïtine) ou des mélanges ou fragments de ceux-ci. Cette composition renferme en option du manganèse qui favorise la production de matrices de tissus conjonctifs. Cette composition renferme également en option des donneurs méthyliques ou des cofacteurs de donneurs méthyliques, tels que la vitamine B12, la vitamine B6, l'acide folique, la diméthylglycine ou la triméthylglycine.

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