Aminosulfonylbiphenyl derivatives

Details Aminosulfonylbiphenyl derivatives Aminosulfonylbiphenyl derivatives

C - Chemistry, Metallurgy

07

C

C07C 311/46 (2006.01) A61K 31/18 (2006.01) A61P 9/10 (2006.01) A61P 29/00 (2006.01) C07C 311/29 (2006.01)

Patent

CA 2399018

The invention relates to compounds of formula (I), wherein R1, R2, R3, R4, W, X and V have the meanings given in the text. Said compounds act as inhibitors of factors Xa and VIIa and can therefore be used for treating and preventing thromboembolitic diseases such as thrombosis, myocardial infarct, arteriosclerosis, infections, apoplexia, angina pectoris, restenosis following angioplasty and intermittent claudication.

L'invention concerne des composés de la formule (I) où R?1¿, R?2¿, R?3¿, R?4¿, W, X et V ont la signification donnée dans le texte. Ces composés agissent comme inhibiteurs des facteurs Xa et VIIa et permettent donc de combattre et de prévenir les maladies thromboemboliques telles que la thrombose, l'infarctus du myocarde, l'artériosclérose, des inflammations, l'apoplexie, l'angine de poitrine, la resténose après angioplastie et la claudication intermittente.

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