Aminotetralin derivative for the therapy of cardiovascular...

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01) A61K 31/136 (2006.01) A61K 31/222 (2006.01) A61K 38/55 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2376715

Left ventricular dysfunction is treated by a process, comprising: administering to a subject suffering from left ventricular remodeling a therapeutically effective amount of 5,6-dihydroxy-2-methylaminotetralin, or 5,6-diisobutyroyl-oxy-2-methyl-aminotetralin, or a pharmaceutically acceptable salt thereof in combination with an angiotensin-converting enzyme inhibitor.

On peut traiter le dysfonctionnement du ventricule gauche par un procédé consistant à administrer souffrant d'un remodelage du ventricule gauche une quantité à effet thérapeutique de 5,6-dihydéroxy-2-méthylaminotétraline, ou de 5,6-diisobutyroyl-oxy-2-méthyl-aminotétraline, l'un de leurs sels pharmacocompatibles, associés à un inhibiteur de l'enzyme de conversion de l'angiotensine.

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