Aminotetralol compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 317/72 (2006.01) A61K 31/13 (2006.01) A61K 31/205 (2006.01) A61K 31/24 (2006.01) C07D 207/32 (2006.01) C07D 207/335 (2006.01) C07D 303/40 (2006.01) C07D 309/20 (2006.01)

Patent

CA 1039297

Aminotetralol Compounds Abstract of the Disclosure: Novel aminotetralol compounds of the formula Image wherein R1 is hydrogen, acyl derived from carboxylic acid, or a hydrocarbon group which may be substituted; -OZ1 is hydroxyl which may be protected; Y is hydrogen, acyl, hydroxyl which may be protected, amino which may be substi- tuted, nitro, cyano or halogen; and n is zero, 1 or 2 with a proviso that when Y is hydrogen or hydroxyl which may be protected, n is not zero, and their salts, have excellent pharmacological activities such as strong bronchodilating activity, They are useful as medicines, for example, for treatment of asthma.

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