Aminothiazoles

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 277/38 (2006.01) C07D 277/42 (2006.01) C07D 307/52 (2006.01) C07D 333/20 (2006.01) C07D 417/12 (2006.01) F16B 15/00 (2006.01)

Patent

CA 1117949

Abstract A series of 2-aryl aminothiazoles and the pharmaceutically acceptable acid addition salts thereof having anti-inflammatory and immune regulant activity are disclosed. Preferred compounds include 2-phenethyl- amino-4-phenyl-thiazole, 2-phenethylamino-4, 5-diphenyl- thiazole, 5-methyl-2-phenethylamino-4-phenyl-thiazole, 2-thenylamino-4-phenyl-thiazole and 2-thenylamino-4- (p-fluorophenyl)-thiazole.

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