Aminothiophenecarboxamides

Details Aminothiophenecarboxamides Aminothiophenecarboxamides

C - Chemistry, Metallurgy

07

D

C07D 333/68 (2006.01) A61K 31/38 (2006.01) C07D 333/38 (2006.01) C07D 333/78 (2006.01) C07D 333/80 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2268886

Aminothiophene carboxylic acid amides having formula (I) and their physiologically harmless salts, wherein R1, R2, R3, R4, R5, A and n have the meaning given in claim 1, demonstrate phosphodiesterase V inhibition and can be used to treat cardiovascular diseases and in therapy for disturbances of potency.

L'invention concerne des amides d'acide carboxylique d'aminothiophène de la formule (I) et leurs sels physiologiquement non toxiques. Dans cette formule, R<1>, R<2>, R<3>, R<4>, R<5>, A et n ont la signification mentionnée dans la revendication 1. Ces amides d'acide carboxylique d'aminothiophène montrent une inhibition dans la région V de la phosphodiestérase et s'utilisent pour traiter des maladies du système cardio-vasculaire et pour soigner des troubles de l'érection .

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