Amiodarone-containing parenteral solution

Details Amiodarone-containing parenteral solution Amiodarone-containing parenteral solution

A - Human Necessities

61

K

A61K 31/343 (2006.01) A61K 31/34 (2006.01) A61K 47/12 (2006.01) A61K 47/20 (2006.01)

Patent

CA 2404298

The present invention provides an amiodarone parenteral solution suitable for intravenous administration without the necessity of dilution. The parenteral solution has an amiodarone concentration from 0.2 to 10 mg/ml and a buffer solution selected from the group consisting of lactate buffer, methanesulfonate buffer, or combinations thereof, the solution having a pH within the range from approximately 2.5 - 4.5.

L'invention concerne une solution parentérale d'amiodarone destinée à l'administration intraveineuse sans nécessité de dilution. Une solution parentérale comprend une concentration d'amiodarone comprise entre 0,2 et 10 mg/ml et une solution tampon sélectionnée parmi le groupe constitué de tampon lactate, tampon méthanesulfonate, ou des combinaisons de ceux-ci. La solution possède un pH compris entre environ 2,5 et 4,5.

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