Amitraz compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/155 (2006.01) A61K 9/08 (2006.01) A61K 31/277 (2006.01) A61K 47/06 (2006.01) A61P 33/14 (2006.01)

Patent

CA 2580577

The present invention provides a stable composition which comprises a non- hydroxyl-group-containing solvent mixture comprising N,N-diethyl-m-toluamide and .gamma.-hexalactone, optionally with dimethyl sulfoxide, eucalyptol and 1- methoxy-2-propyl acetate; and an effective amount of each of amitraz and at least one additional parasiticidal compound, such as R-28153. Said composition allows for high concentrations of a mixture of parasiticidal agents in a single application and is useful for treating and controlling parasiticidal infection and infestation in a homeothermic animal.

L'invention concerne une composition stable qui comprend mélange de solvant contenant un groupe non hydroxyle comprenant N, N-diéthyl-m-toluamide et .gamma.-hexalactone, éventuellement avec diméthylsulfoxyde, eucalyptol et 1-méthoxy-2-propyl acétate ainsi qu'une quantité efficace d'amitraze et d'au moins un composé antiparasitaire supplémentaire tel que R-28153. Cette composition permet de grandes concentrations d'un mélange d'agents antiparasitaires dans une unique application et est utile pour le traitement et la maîtrise d'infections et infestations antiparasitaires chez un animal homéotherme.

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