Amlodipine hemifumarate

Details Amlodipine hemifumarate Amlodipine hemifumarate

C - Chemistry, Metallurgy

07

D

C07D 211/90 (2006.01) A61K 31/4418 (2006.01) A61K 31/4422 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2433181

Amlodipine fumarate salt compounds are useful as calcium channel blockers and in treating or preventing angina or hypertension. The fumarate salts avoid the formation of certain potential impurities that have been found to be associated with amlodipine maleate.

L'invention concerne des composés de sels de fumarate d'amlodipine qui sont utiles en tant qu'agents bloquants du canal calcique et pour le traitement et la prévention de l'angine de poitrine et de l'hypertension. Les sels de fumarate permettent d'éviter la formation de certaines impuretés potentielles découvertes en association avec le maléate d'amlodipine.

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