Ammine-alicyclic amine-platinum complexes and antitumor agents

Details Ammine-alicyclic amine-platinum complexes and antitumor agents Ammine-alicyclic amine-platinum complexes and antitumor agents

C - Chemistry, Metallurgy

07

F

167/119, 260/292

C07F 15/00 (2006.01) A61K 31/555 (2006.01)

Patent

CA 1327039

Abstract of the Disclosure A compound of the formula (I) : Image (I) (wherein R is hydrogen, C1-C5 alkyl, hydroxy, carboxy, C1-C5 alkoxy, halogen or oxo; m is an integer from 2 to 7; X and Y each is chlorine or nit?rato ligand, or taken together from -OCOCH(R1)O-, OCOCOO- Image or Image R1 is hydrogen, C1-C5 alkyl, hydroxymethy, halomethyl or phenyl; R2 is hydrogen or C1-C5 alkyl; and n is an integer from 2 to 5), being useful as antitumor agents is provided.

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