Amnion-derived cell compositions, methods of making and uses...

Details Amnion-derived cell compositions, methods of making and uses... Amnion-derived cell compositions, methods of making and uses...

C - Chemistry, Metallurgy

12

N

C12N 5/073 (2010.01) C12N 5/071 (2010.01) C12N 5/077 (2010.01) A61K 8/98 (2006.01) A61K 35/12 (2006.01) A61P 17/02 (2006.01)

Patent

CA 2602684

The invention is directed to substantially purified amnion-derived cell populations, compositions comprising the substantially purified amnion-derived cell populations, and to methods of creating such substantially purified amnion-derived cell populations, as well as methods of use. The invention is further directed to antibodies, in particular, monoclonal antibodies, that bind to amnion- derived cells or, alternatively, to one or more amnion-derived cell surface protein markers. The invention is further directed to methods for producing the antibodies, methods for using the antibodies, and kits comprising the antibodies.

L'invention concerne des populations cellulaires amniotiques sensiblement purifiées, des compositions comprenant ces populations, et des méthodes de création et d'utilisation desdites populations cellulaires sensiblement purifiées. L'invention concerne également des anticorps, en particulier des anticorps monoclonaux, qui se lient aux cellules amniotiques ou, en variante, à un ou plusieurs marqueurs de protéine de surface des cellules amniotiques. L'invention concerne en outre des méthodes de production des anticorps, des méthodes d'utilisation des anticorps et des trousses contenant les anticorps.

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