Amniotic cells and methods for use thereof

Details Amniotic cells and methods for use thereof Amniotic cells and methods for use thereof

C - Chemistry, Metallurgy

12

N

C12N 5/22 (2006.01) A61K 48/00 (2006.01) A61P 9/10 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/66 (2006.01) C12N 15/85 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2620946

The present invention provides a population of human amniotic cells comprising lentiviral vectors with at least one exogenous gene element and methods for making such cells. The cells of the invention can be used for treating diseases such as those related to neurologic disorders including, for example, cerebral ischemia, cerebral vascular disease, central nervous system injuries, genetic diseases of the nervous system, degenerative diseases of the cerebral nervous system, tumors of the cerebral nervous system and combinations thereof.

L'invention concerne une population de cellules amniotiques humaines comprenant des vecteurs lentiviraux qui contiennent au moins un élément génétique exogène et des méthodes permettant de fabriquer ces cellules. Les cellules selon l'invention peuvent être utilisées pour traiter des maladies telles que des maladies liées aux troubles neurologiques, par exemple, l'ischémie cérébrale, la maladie vasculaire cérébrale, les lésions du système nerveux central, les maladies génétiques du système nerveux, les maladies dégénératives du système nerveux cérébral, les tumeurs du système nerveux cérébral et des combinaisons de ces dernières.

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