A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/12 (2006.01)
Patent
CA 2623940
Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF-.beta. signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis- related diseases.
Il a été démontré que des compositions comprenant une combinaison de composantes biologiques spécifiques, exercent un certain nombre d'effets favorables sur les cellules mammifères, y compris la modulation de la signalisation TGF-ß, l'apoptose, et la prolifération de cellules mammifères, ainsi que la diminution de l'inflammation chez des souris. Ces composantes peuvent être obtenues d'une manière commerciale, ou peuvent être préparées à partir de tissus biologiques tels que des tissus placentaires. Des préparations de membrane amniotique (AM) placentaire décrites dans l'invention, comprennent des morceaux de AM, des extraits de AM, la gelée de AM, le stroma de AM, et des mélanges de ces compositions avec des composantes supplémentaires. Les compositions peuvent être utilisées pour traiter différents troubles tels que des troubles de la cicatrisation, des troubles inflammatoires et des troubles liés à l'angiogenèse.
He Hua
Li Wei
Tseng Scheffer
Gowling Lafleur Henderson Llp
Tissuetech Inc.
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