Amorphous and crystalline forms of losartan potassium and...

Details Amorphous and crystalline forms of losartan potassium and... Amorphous and crystalline forms of losartan potassium and...

C - Chemistry, Metallurgy

07

D

C07D 257/04 (2006.01) A61K 31/41 (2006.01) C07D 403/10 (2006.01)

Patent

CA 2465597

This invention relates to novel amorphous losartan potassium, novel losartan potassium in a crystalline form that is a hydrate, novel crystalline losartan potassium Form IV and solvates thereof, novel crystalline losartan potassium Form V and solvates thereof, to processes for their preparation, to compositions containing them and to their use in medicine. This invention further relates to a novel process for preparing crystalline losartan potassium Form I and Form II.

L'invention concerne un nouveau losartan potassique amorphe, un nouveau losartan potassique sous forme cristalline qui est un hydrate, un nouveau losartan potassique cristallin de forme IV et des solvats de celui-ci, et un nouveau losartan potassique cristallin de forme V et des solvats de celui-ci, leur procédé de préparation, des compositions contenant lesdits losartans potassiques et leur utilisation en médicine. L'invention concerne également un nouveau procédé de préparation du nouveau losartan potassique cristallin de forme I et de forme II.

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