Amorphous and polymorphic forms of telmisartan sodium

Details Amorphous and polymorphic forms of telmisartan sodium Amorphous and polymorphic forms of telmisartan sodium

C - Chemistry, Metallurgy

07

D

C07D 235/20 (2006.01) A61K 31/4184 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2583694

Provided is (Formula (I)) the amorphous form of telmisartan sodium and the preparation thereof. Also provided are the telmisartan sodium polymorph crystal Forms 0 to XIII and XV to XX and preparations thereof. Also provided are pharmaceutical composition of amorphous and polymorphic forms of telmisartan sodium or mixtures thereof, and methods of treatment of a mammal in need thereof.

L'invention concerne une forme amorphe de sodium telmisartan, ainsi qu'un procédé de préparation associé. L'invention concerne également les formes cristallines polymorphes 0 à XIII et XV à XX de sodium telmisartan, ainsi que des procédés de préparation associés. L'invention concerne encore une composition pharmaceutique de formes amorphes et polymorphes de sodium telmisartan ou de mélanges de celles-ci, ainsi que des méthodes de traitement d'un mammifère nécessitant un tel traitement.

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