Amorphous asenapine and processes for preparing same

Details Amorphous asenapine and processes for preparing same Amorphous asenapine and processes for preparing same

C - Chemistry, Metallurgy

07

D

C07D 493/04 (2006.01) A61K 31/407 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2667668

This disclosure relates to amorphous asenapine and pharmaceutically acceptable complexes, salts, solvates and hydrates thereof, to solid pharmaceutical compositions containing it, and to its use to treat central nervous system disorders, including schizophrenia and bipolar disorder. This disclosure also relates to methods and materials for preparing amorphous asenapine and pharmaceutical compositions which contain it.

La présente invention concerne de l'asénapine amorphe et des complexes, sels, solvates et hydrates pharmaceutiquement acceptables de cette substance, ainsi que des compositions pharmaceutiques solides qui la contiennent et son utilisation pour traiter des troubles du système nerveux central, notamment la schizophrénie et le trouble bipolaire. La présente invention concerne également des procédés et des matériaux permettant de préparer l'asénapine amorphe ainsi que des compositions pharmaceutiques qui la contiennent.

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