Amorphous lercanidipine hydrochloride

Details Amorphous lercanidipine hydrochloride Amorphous lercanidipine hydrochloride

C - Chemistry, Metallurgy

07

D

C07D 211/90 (2006.01) A61K 31/435 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2598016

The invention provides a substantially pure amorphous lercanidipine hydrochloride having a purity of at least 95 % pure, preferably at least about 97% pure, more preferably at least about 99% pure, and still more preferably at least about 99.5 % pure. The invention further provides methods of preparing substantially pure amorphous lercanidipine, and pharmaceutical compositions containing the substantially pure amorphous lercanidipine.

L'invention se rapporte à du chlorhydrate de lercanidipine amorphe sensiblement pur présentant une pureté d'au moins 95 %, plutôt 97 %, de préférence d'au moins 99 %, et idéalement d'environ 99,5 %. Cette invention porte sur des procédés de préparation de lercanidipine amorphe sensiblement pur, et sur des compositions pharmaceutiques contenant ce lercanidipine amorphe sensiblement pur.

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