Amorphous (quinolin-2-ylmethoxy) indoles

Details Amorphous (quinolin-2-ylmethoxy) indoles Amorphous (quinolin-2-ylmethoxy) indoles

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2082568

A form of 3-[N-(p-chlorobenzyl)-3- (t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]- 2,2-dimethylpropanoic acid sodium salt, obtained by freeze or spray drying, is more soluble in water than the crystalline form thereof. The compound is useful as an anti-asthmatic, anti-allergic, anti-inflam- matory, or cytoprotective agent. It is also useful in treating; diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.

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