Amorphous valganciclovir hydrochloride

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 473/18 (2006.01) A61K 31/52 (2006.01)

Patent

CA 2537132

The present invention relates to an amorphous form of valganciclovir hydrochloride and the pharmaceutical compositions thereof. The amorphous form can be directly prepared by spray-drying or azeotropic distillation of reaction mass. The amorphous form is useful in treating viral infections, for example, herpes simplex and cytomegalovirus.

Forme amorphe de chlorhydrate de valganciclovir et compositions pharmaceutiques la contenant. Cette forme amorphe peut être directement obtenue par séchage par pulvérisation ou distillation azéotrope d'une matière de réaction. Elle est utile pour le traitement d'infections virales, par exemple les infections à herpès simplex et à cytomégalovirus.

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