Amphiphilic block copolymers and their use

Details Amphiphilic block copolymers and their use Amphiphilic block copolymers and their use

C - Chemistry, Metallurgy

09

J

C09J 183/12 (2006.01) A61L 27/14 (2006.01) C08G 18/61 (2006.01) C08G 77/452 (2006.01) C08G 77/458 (2006.01) C08G 77/46 (2006.01) G02B 1/04 (2006.01)

Patent

CA 2589887

The present invention relates to amphiphilic block copolymers comprising at least one block of hydrophilic units and at least one block of hydrophobic units, wherein at least one hydrophobic block contains siloxane units. The present invention may be particularly useful as a tissue adhesive or as a coating for an intraocular lens (IOL). As an IOL coating, copolymers according to the invention may be used, for example, to promote tissue adhesion for the prevention of posterior capsule opacification.

L'invention concerne des copolymères blocs amphiphiles comprenant au moins un bloc d'unités hydrophiles et au moins un bloc d'unités hydrophobes, au moins un bloc hydrophobe contenant des unités siloxane. Cette invention peut être particulièrement utile en tant qu'adhésif tissulaire ou en tant que revêtement de lentille intra-oculaire (IOL). Sous cette dernière forme, on peut mettre en application ces copolymères, par exemple, afin de promouvoir l'adhérence tissulaire dans le but d'empêcher l'opacification de la capsule postérieure.

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