Amphiphilic derivatives for the production of vesicles,...

C - Chemistry – Metallurgy – 07 – C

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C07C 69/76 (2006.01) A61K 9/127 (2006.01) A61K 47/18 (2006.01) A61K 47/24 (2006.01) A61K 9/107 (2006.01)

Patent

CA 2434409

Amphiphilic derivatives composed of at least one fatty acid chain are derived from natural vegetable oils such as vernonia oil, lesquerella oil and castor oil, in which the several reactive groups such as epoxy, hydroxy and double bonds can be modified to polar and ionic groups. The head group of the amphiphilic derivative may be in the main fatty acid chain or in a side chain. The amphiphiles are useful for the formation of vesicles and micelles and for use as complexants and surfactants.

L'invention concerne des dérivés amphiphiles contenant au moins une chaîne d'acides gras obtenus à partir d'huiles végétales naturelles, p. ex. huiles de vernonia, de lesquerella et de castor, dans lesquels plusieurs groupes réactifs, p. ex. époxy, hydroxy et liaisons doubles, peuvent être transformés en groupes polaires et ioniques. Le groupe de tête du dérivé amphiphile peut être dans la chaîne d'acides gras principale ou dans une chaîne latérale. Les amphiphiles sont utiles pour la formation de vésicules et de micelles, et comme complexants et tensioactifs.

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