Amphiphilic derivatives of guanidine

Details Amphiphilic derivatives of guanidine Amphiphilic derivatives of guanidine

C - Chemistry, Metallurgy

12

N

C12N 15/88 (2006.01) A61K 9/127 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07C 279/08 (2006.01)

Patent

CA 2176715

Guanidine-based amphiphiles are provided that are non-toxic to the host mammal, especially a human host. The amphiphiles are used to produce liposomes useful as carriers for delivering macromolecules intracellularly.

L'invention se rapporte à des amphiphiles à base de guanidine non toxiques pour un mammifère hôte, en particulier l'homme. Ces amphiphiles sont utilisés pour produire des liposomes aptes à être utilisés comme vecteurs destinés à l'apport intracellulaire de macromolécules.

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