Amphiphilic derivatives of piperazine

Details Amphiphilic derivatives of piperazine Amphiphilic derivatives of piperazine

C - Chemistry, Metallurgy

12

N

C12N 15/88 (2006.01) A61K 9/127 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07D 295/088 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2176714

Novel, heterocyclic cationic amphiphile and compounds thereof are prepared that are degraded in vivo. Liposomes are produced from the cations that are used as carriers for delivering macromolecules intracellularly and may be targeted to a specific cell type.

On prépare un nouvel amphiphile cationique hétérocyclique et des composés de ce dernier qui sont dégradés in vivo. On produit des liposomes à partir des cations qui servent de supports pour apporter des macromolécules à l'intérieur des cellules et qui peuvent être ciblés contre un type de cellule spécifique.

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