Amphiphilic imidazolinium derivatives

Details Amphiphilic imidazolinium derivatives Amphiphilic imidazolinium derivatives

C - Chemistry, Metallurgy

12

N

C12N 15/88 (2006.01) A61K 9/127 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07C 279/08 (2006.01) C07D 233/54 (2006.01) C07D 233/60 (2006.01)

Patent

CA 2176713

Amphiphiles containing an imidazolinium ring system are provided that are non-toxic to the host mammal. The amphiphiles are used to produce liposomes useful as carriers for delivering macromolecules intracellularly.

L'invention a pour objet des amphiphiles contenant un système cyclique d'imidazolinium, qui sont non toxiques pour le mammifère hôte. Ces amphiphiles sont utilisés pour produire des liposomes utiles comme vecteurs pour apporter des macromolécules à l'intérieur des cellules.

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