Amphiphilic polynorbornene derivatives and methods of using...

C - Chemistry – Metallurgy – 08 – F

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C08F 32/08 (2006.01) A01N 43/90 (2006.01) A01P 1/00 (2006.01) A61K 31/787 (2006.01) A61L 2/16 (2006.01) C07D 209/52 (2006.01)

Patent

CA 2577429

Polynorbornene derivatives exhibiting antibacterial activity and low hemolytic activity are described herein. Antimicrobial compositions and pharmaceutical compositions comprising polynorbonene derivatives and methods of using the same are also described. Such compositions, which exhibit substantial antibacterial activity and low hemolytic activity, may be suitable for material applications and therapeutic uses.

L'invention concerne des dérivés de polynorbornène présentant une activité antibactérienne et une activité hémolytique faible, des compositions antimicrobiennes et des compositions pharmaceutiques contenant des dérivés de polynorbornène, ainsi que des méthodes d'utilisation associées. De telles compositions, qui présentent une activité antibactérienne sensible et une activité hémolytique faible, peuvent être appropriées à des applications matérielles et à des utilisations thérapeutiques.

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