Amphiphilic prodrugs

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/48 (2006.01)

Patent

CA 2384645

The present invention provides amphiphilic prodrugs comprising a therapeutic compound conjugated to an PEG-oligomer/polymer and methods for using said prodrugs to enable oral drug delivery and/or delivery of drugs across the blood brain barrier into the central nervous system.

L'invention concerne des promédicaments amphiphiles renfermant un composé thérapeutique conjugué à un oligomère/polymère de polyéthylèneglycol, et des procédés relatifs à l'utilisation de ces promédicaments pour leur administration par voie orale et/ou au travers de la barrière hémato-encéphalique dans le système nerveux central.

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