Amphiphilic pyridinium compounds, method of making and use...

A - Human Necessities – 61 – K

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A61K 31/4425 (2006.01) C07D 213/20 (2006.01) C07D 213/30 (2006.01)

Patent

CA 2530075

The present invention is directed to the amphiphilic pyridinium compounds, such as for suppressing IL-8 secretion and production. The present invention further provides methods of making and using such compounds for the treatment of the IL-8 related diseases, such as cystic fibrosis.

L'invention concerne des composés de pyridinium amphiphiles destinés, par exemple, à supprimer la sécrétion et la production de IL-8. L'invention concerne en outre des procédés de fabrication et d'utilisation de ces composés dans le traitement de maladies liées à IL-8 telles que la mucoviscidose.

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