Amphiphilic star-like or scorpion-like macromolecules,...

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A61K 9/51 (2006.01) A61K 31/74 (2006.01) A61K 31/785 (2006.01) A61K 31/795 (2006.01)

Patent

CA 2555033

Biomedical uses of amphiphilic macromolecules include the use of such macromolecules in the form of nanoparticle formulations for the sequestration and/or removal of LDL, and for the treatment and prevention of atherosclerosis and atherosclerotic development. The invention also provides the use of amphiphilic macromolecule encapsulates for treating diseases including cancer and inflammation, as well as targeted amphiphilic macromolecules and their use in therapy.

Des utilisations biomédicales de macromolécules amphiphiles comprennent l'utilisation de ces macromolécules sous forme de préparations de nanoparticules destinées à la séquestration et/ou l'extraction de LDL et, au traitement et la prévention de l'athérosclérose et du développement de l'athérosclérose. Cette invention concerne aussi l'utilisation de gélules de macromolécules amphiphiles destinées au traitement de maladie comprenant le cancer et des inflammations ainsi que des macromolécules amphiphiles ciblées et leur utilisation thérapeutique.

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