C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/08 (2006.01) A61K 41/00 (2006.01) C07D 209/00 (2006.01) C07D 259/00 (2006.01) C07D 487/22 (2006.01) C09B 47/04 (2006.01)
Patent
CA 2525447
Disclosed herein are novel trisulfonated tribenzo-mononahptho-porphyrazines, processes for making them and their application as improved photosensitizing drugs for the treatment of various medical conditions by photodynamic therapy (PDT). These water-soluble amphiphilic porphyrazines are substituted with different alkylyl, aryl, aminoalkyl and aminoaryl groups, with or without carboxyl moeity.
L'invention concerne de nouvelles tribenzo-mononahptho-porphyrazines trisulfonées, ainsi que leurs procédés de production et leur application en tant que médicaments photosensibilisants dans le traitement de nombreux états pathologiques médicaux par thérapie photodynamique (TPD). Lesdites porphyrazines amphiphiles, solubles dans l'eau sont substituées par différents groupes alkylyle, aryle, aminoalkyle et aminoaryle, avec ou sans fraction carboxyle.
Ali Hasrat
Cauchon Nicole
Hassessian Haroutioun Minas
Tian Hongjian
Van Lier Johannes E.
Hopital Maisonneuve-Rosemont
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
R. S. E. M. Societe En Commandite
Societe de Commercialisation Des Produits de La Recherche Appliq
Universite de Sherbrooke
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