C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/305, 530/5.0
C07D 295/14 (2006.01) C07D 233/54 (2006.01) G01N 27/447 (2006.01)
Patent
CA 1139304
ABSTRACT OF THE DISCLOSURE A water-soluble ampholyte which comprises the reaction product between a) one or more compounds selected from the group comprising certain amino-acids, hydroxylamine, an amine of the formula Image wherein R1 is hydrogen, the group H2N-(CH2)n-, wherein n is an integer 2 - 6, or the group H2N-(CH2)3-NH-(CH2)3-. R2 and R3 are the same or different and each representing hydrogen, methyl, ethyl or hydroxyethyl or together with the intermediate nitrogen atom form certain heterocyclic groups, and certain di- and tripeptides, at least one of these compounds being one which contains at least one carboxyl group, or salts of the aforementioned compounds, and b) at least one bifunctional alkylating agent containing a straight or branched alkylene chaln havlng 2 - 10 carbon atoms and which chain may be substituted with certain substituents and/or be broken by 1 - 3 oxygen atoms with certain conditions, in a molar relationship between b) and a) of 1:2 - 9:10.
300016
Pharmacia Fine Chemicals Ab
Ridout & Maybee Llp
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