Amphotericin b methyl ester salts

Details Amphotericin b methyl ester salts Amphotericin b methyl ester salts

C - Chemistry, Metallurgy

07

H

260/230.35

C07H 17/08 (2006.01) C07C 53/06 (2006.01) C07C 53/10 (2006.01) C07C 53/126 (2006.01) C07C 55/07 (2006.01) C07C 55/08 (2006.01) C07C 55/10 (2006.01) C07C 55/12 (2006.01) C07C 55/14 (2006.01) C07C 59/08 (2006.01) C07C 59/255 (2006.01) C07D 207/28 (2006.01)

Patent

CA 1085828

Abstract Certain amphotericin B methyl ester salts, i.e., salts formed by reaction with mono and dicarboxylic amino acids (such as aspartic acid, or glutamic acid or pyroglu- tamic acid) are provided and have been found to be more readily water-soluble and at least as stable and active as the parent ester compound.

270985

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