A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 9/51 (2006.01) A61K 31/282 (2006.01) A61K 31/4188 (2006.01) A61K 31/704 (2006.01) A61K 31/721 (2006.01) A61K 31/74 (2006.01) A61P 35/04 (2006.01)
Patent
CA 2506842
The present invention relates to the delivery of drug, peptide and protein pharmaceuticals using a biotin-mediated uptake system. More particularly the invention relates to the amplification of active substance delivery with the biotin uptake system using a biotin-active substance-polymer conjugate or a biotin-nanoparticle conjugate. The invention also relates to processes for preparing the conjugates, pharmaceutical and diagnostic compositions containing same and methods of diagnosis and treatment involving the conjugates.
L'invention concerne l'administration de médicaments, de produits pharmaceutiques à base de peptides et de protéines à l'aide d'un système d'absorption médié par la biotine. Plus précisément, l'invention concerne l'amplification de l'administration de substances actives, le système d'absorption de biotine utilisant un conjugué biotine-substance active-polymère ou un conjugué biotine-nanoparticules. L'invention concerne également des processus de préparation des conjugués, des compositions pharmaceutiques et diagnostiques les contenant ainsi que des procédés de diagnostic et de traitement impliquant ces conjugués.
Mcewan John
Russell-Jones Gregory
Access Pharmaceuticals Australia Pty Ltd
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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