A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/76 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/18 (2006.01) A61K 31/19 (2006.01) A61K 31/4353 (2006.01) A61K 31/4406 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2706750
The invention provides methods for treating cancer cells in a host by infecting the cancer cells with one or more strains of oncolytic virus, in conjunction with treating the host with an amount of an HDI that is effective to augment the cancer-cell-specific oncolytic infection.
La présente invention concerne des procédés permettant de traiter des cellules cancéreuses chez un hôte en infectant les cellules cancéreuses avec une ou plusieurs souches de virus oncolytiques, conjointement au traitement de l'hôte avec une quantité d'un inhibiteur d'histone désacétylase qui est efficace pour augmenter l'infection oncolytique spécifique aux cellules cancéreuses.
Abdelbary Hesham
Bell John Cameron
Diallo Jean-Simon
Hiscott John
Nguyen Lien-Anh
Ottawa Health Research Institute
Ottawa Hospital Research Institute
Smart & Biggar
LandOfFree
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