Amplification of nucleic acids with electronic detection

Details Amplification of nucleic acids with electronic detection Amplification of nucleic acids with electronic detection

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2319170

The invention relates to compositions and methods useful in the detection of nucleic acids using a variety of amplification techniques, including both signal amplification and target amplification. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the nucleic acid, either directly or indirectly, to allow electronic detection of the ETM using an electrode.

L'invention porte sur des compositions et des procédés utiles dans la détection des acides nucléiques à l'aide de diverses techniques d'amplification telles que l'amplification des signaux et l'amplification de la cible. La détection commence par l'utilisation d'une fraction de transfert d'électrons qui est associée à l'acide nucléique, soit directement, soit indirectement, pour permettre la détection électronique de cette fraction de transfert d'électrons à l'aide d'une électrode.

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