Amplification of nucleic acids with electronic detection

Details Amplification of nucleic acids with electronic detection Amplification of nucleic acids with electronic detection

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 27/30 (2006.01)

Patent

CA 2379693

The invention relates to compositions and methods useful in the detection of nucleic acids using a variety of amplification techniques, including both signal amplification and target amplification. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the nucleic acid, either directly or indirectly, to allow electronic detection of the ETM using an electrode.

L'invention concerne des compositions et des procédés utiles dans la détection d'acides nucléiques au moyen de diverses techniques d'amplification, y compris l'amplification de signal et l'amplification de cible. La détection est mise en oeuvre à l'aide d'une fraction de transfert d'électrons (ETM) qui est associée à l'acide nucléique, directement ou indirectement, pour permettre une détection électronique de ladite ETM par une électrode.

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