C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/705 (2006.01) C12N 9/12 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2506243
There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing genes, which are amplified in many types of cancer. The amplified genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or as vaccines; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.
L'invention concerne des méthodes et des compositions destinées au diagnostic, à la prévention et au traitement de tumeurs et de cancers chez des mammifères, tels que l'homme, au moyen de gènes qui sont amplifiés dans de nombreux types de cancer. Les gènes amplifiés, leurs produits protéiques exprimés et des anticorps sont utilisés à des fins de diagnostic ou comme cibles pour le traitement de cancers, ou encore comme vaccins. Ils sont également utilisés pour identifier des composés et des réactifs utiles pour le diagnostic, la prévention et le traitement de cancers.
Li Jing
Powers Scott
Sin Wun Chey
Yang Jianxin
Amgen Inc.
Smart & Biggar
LandOfFree
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