C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/16 (2006.01) A61K 38/22 (2006.01) A61K 38/23 (2006.01) C07K 14/575 (2006.01) C07K 14/585 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2580991
The present invention relates to Amylin Family Polypeptide-6 (AFP-6) analogs, which include derivatives and fragments, related nucleic acids, expression constructs, host cells, and processes for recombinant production of the AFP-6 analogs. The AFP-6 analogs of the invention include one or more amino acid sequence modifications. In addition, methods and compositions are disclosed to treat and prevent conditions such as metabolic and cardiovascular disorders, e.g., obesity, diabetes, metabolic syndrome, myocardial ischemia, and increased cardiovascular risk.
La présente invention porte sur des analogues de la famille de l'amyline du polypeptide-6 (AFP-6), ces analogues comprenant des dérivés et des fragments, des acides nucléiques apparentés, des produits de recombinaison d'expression, des cellules hôtes et des procédés de production par recombinaison des analogues d'AFP-6. Les analogues d'AFP-6 de l'invention comportent une ou plusieurs modifications de séquences d'acides aminés. Ces procédés et ces compositions permettent également de traiter et de prévenir des états tels que les maladies métaboliques et cardio-vasculaires, par exemple, l'obésité, le diabète, le syndrome métabolique, l'ischémie myocardique et les risques cardio-vasculaires accrus.
Erickson Mary
Ghosh Soumitra
Mcquaid Sarah
Pittner Richard
Srivastava Ved
Amylin Pharmaceuticals Inc.
Smart & Biggar
LandOfFree
Amylin family polypeptide-6 (afp-6) analogs and methods of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Amylin family polypeptide-6 (afp-6) analogs and methods of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amylin family polypeptide-6 (afp-6) analogs and methods of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1528855