Amyloid plaque aggregation inhibitors and diagnostic imaging...

Details Amyloid plaque aggregation inhibitors and diagnostic imaging... Amyloid plaque aggregation inhibitors and diagnostic imaging...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 49/00 (2006.01) A61K 51/00 (2006.01) A61K 51/04 (2006.01) A61P 25/28 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07F 7/22 (2006.01) C07F 13/00 (2006.01)

Patent

CA 2444214

This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.

Cette invention concerne un procédé d'imagerie de dépôts amyloïdes et des composés marqués, ainsi que des procédés de production de composés marqués utilisés dans l'imagerie de dépôts amyloïdes. Cette invention porte également sur des composés et des procédés de fabrication de composés servant à inhiber l'agrégation de protéines amyloïdes formant des dépôts amyloïdes, ainsi que sur un procédé de diffusion d'un agent thérapeutique sur des dépôts amyloïdes.

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