Amyotrophic lateral sclerosis treatment with...

A - Human Necessities – 61 – K

Patent

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A61K 31/505 (2006.01) A01N 43/54 (2006.01)

Patent

CA 2487885

A method of treating, preventing, or inhibiting ALS, in a subject in need of such treatment, inhibition or prevention. The method comprises administering to a subject one or more cyclooxygenase-2 selective inhibitor(s) or isomer(s) or pharmaceutically acceptable salt(s), ester(s), or prodrug(s) thereof, in combination with one or more second drugs, wherein the amount of the cyclooxygenase-2 selective inhibitor(s) or isomer(s) or pharmaceutically acceptable salt(s), ester(s), or prodrug(s) thereof in combination with the amount of second drug(s) constitutes an ALS treatment, inhibition or prevention effective amount.

L'invention concerne une méthode permettant de traiter, prévenir ou inhiber la sclérose amyotrophique latérale (ALS) chez un sujet ayant besoin de traitement, de prévention ou d'inhibition. Ladite méthode consiste à administrer à un sujet un ou plusieurs inhibiteur(s) sélectif(s) de la cyclooxygénase-2, un ou des isomère(s), un ou des sels pharmaceutiquement acceptables, un ou des ester(s) ou un ou des promédicament(s) de ceux-ci en combinaison avec un ou plusieurs médicaments. La quantité d'inhibiteurs sélectifs de la cyclooxygénase-2, d'isomère(s), d'ester(s), de sel(s) ou de promédicament(s) de ceux-ci en combinaison avec la quantité de second médicament(s) constitue une quantité efficace pour traiter, prévenir ou inhiber l'ALS.

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