A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/55 (2006.01) A61K 9/00 (2006.01) A61K 38/05 (2006.01) A61P 7/02 (2006.01) A61K 47/18 (2006.01) A61K 47/20 (2006.01)
Patent
CA 2504480
An aqueous pharmaceutical formulation comprising the thrombin inhibitor HOOC- CH2-(R)-Cgl-Aze-Pab (melagatran), or a pharmaceutically-acceptable derivative thereof, a process for the preparation of such a pharmaceutical formulation, the use of such a formulation in the treatment of thromboembolism as well as a method of treating a patient in need of antithrombotic treatment and thromboembolism by using said formulation via nasal administration.
L'invention concerne une préparation pharmaceutique aqueuse contenant l'inhibiteur de la thrombine HOOC-CH¿2?-(R)-Cgl-Aze-Pab (melagatran), ou un dérivé pharmaceutiquement acceptable de celui-ci, un procédé permettant de préparer une telle formulation pharmaceutique, l'utilisation d'une telle formulation pour le traitement des thrombo-embolies, ainsi qu'une méthode permettant de traiter un patient nécessitant un traitement antithrombotique, et les thrombo-embolies au moyen desdites formulations administrées par voie nasale. ? ¿
Edman Peter
Wingstrand Karin
Astrazeneca Ab
Fetherstonhaugh & Co.
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